SD is a key objective for European science and technology (S&T) cooperation, both within Europe and in European partnerships with countries and international organisations around the world. This chapter examines how SD concepts are embedded within European policies on S&T partnership, both explicitly and implicitly, and pertaining both to intra-European partnerships and those between the European Union (EU) and the rest of the world. The authors suggest how the European model for S&T cooperation might be adapted to develop global partnerships in a balanced, long-term and sustainable way.